The commonality of spider webs on different plants and animals’ bodies is an object of fascination. The scientific community has spent years trying to analyze the spider webs on plants and animals, as well as humans. This common property of spider webs on different organisms is used as a test subject for pharmacological intervention. The common properties of spider webs on different animals and plants make them ideal for testing pharmacotherapies. The results of this experiment are used in drug development, aiming to make new safe and efficient drugs.
Spider webs on drugs can be used as a test of dose in determining the concentration of pharmacologically active agents in the blood. The length and intensity of spider webs on the animal can also be studied to evaluate drug toxicity. For instance, the concentration of caffeine on spider webs on caffeine-naive (Cessiaca Cambogia) rats was approximately threefold greater than that on non-naive (Cissampelos pareira) rats. The concentration of spider webs on drugs can also be studied to evaluate the effect of long-term administration of small doses of pharmacological agents. In this case, Jessica can be considered as a control plant in the caffeine experiment since it does not show caffeine tolerance.
In the spider webs on drugs experiment, the spider is killed and the web-building medium is withdrawn from its body. The spider is then tested for reaction to seven days ago the administration of a variety of psychoactive drugs. Seven days ago, the spider received a dose of Caffeine, cocaine, alcohol, amyl nitric acid, ketamine, mazhangand, Ambien, propofol, and phenobarbital, all in the form of oral medications. It was found that spider ingestion had no effect on behavior or appetite, but did show a decreased responding tendency to stress (by decreasing the duration of the test). Further, there were no changes in the levels of neurotransmitters detected in the brain; i.e., there was no change in the concentrations of noradrenaline and dopamine, nor in their receptors detected on the synapses of the brain.
In the second set of data, the effects of seven days ago the administration of Caffeine on spider webs on human subjects were evaluated. This time, the spider received a dose of cocaine, alcohol, amyl nitric acid, ketamine, mazhangand, propofol, and Phenobarbital, in the form of oral drugs. The test was performed five days ago at the laboratory of neurosurgery of the university. The results showed that there were no effects of Caffeine on the behavior or appetite of the spider. In addition, there were no changes in the levels of neurotransmitters detected in the brain; i.e., there were no changes in the concentrations of noradrenaline and dopamine, nor in their receptors detected on the synapses of their brain.
Thus, the results showed that spider-building, a behavior related to anxiety and frustration, is affected by Caffeine. These results are significant for two reasons: first, the results demonstrate that spider-building is affected by external stimuli, not by inner factors, such as internal feelings; and second, the present study was performed on only one spider, rather than on a number of animals. It is now well established that spider-building, a behavior related to frustration and anxiety, is affected by Caffeine. It is therefore concluded that Caffeine has central nervous system effects.
The present study took place in the laboratory of neurosurgery of the university. At that time, the spider C lexicon was used as an experimental subject. The spider was fed with a piece of caffeine mixed with water and was allowed to crawl about in a box, without being tied to any object. Several days later, a patch was attached to the spider, through which the spider could drink a portion of water. After several days, a web (usually a square or oblong-shaped one) formed on the spot where the spider had consumed the water.
When this spider web formed, the spider’s behavior was photographed, and the spider was then marked according to its behavior (i.e., aggressive, passive, etc.) at the time of the photo session. At the next session, the spider’s behavior was compared with the spider’s photograph, and a different color was chosen. This spider web was then analyzed for differences between the spider’s behavior at the time of the photograph and at the time of its analysis. The results showed a significant increase (p = 0.000) in the proportion of squares containing a spider web at the time of drinking the caffeine compared to the interval when the spider did not drink caffeine.
Because this pattern was seen on an experimental day, this provides strong evidence that spider webs on drugs can be formed on a normal basis when caffeine is consumed. In addition, it also demonstrates that such webs are common even on non-caffeinated substances. Moreover, the spider’s behavior does not change despite the amount of caffeine ingested. Therefore, spiders are able to construct webs on drugs and pass them on to humans even when the drugs are controlled by the patient.